What is a symptom of Cushing's syndrome?

Cushing's syndrome is characterized by an overproduction of cortisol, a hormone that plays a crucial role in various bodily functions. One of the most notable physical symptoms associated with this condition is the development of a "moon face," which refers to the rounding of the face and swelling in the cheeks. This change in facial appearance occurs due to fat deposits and fluid retention, both of which are influenced by high cortisol levels.

This symptom is particularly distinctive and is often a hallmark sign that helps healthcare providers in diagnosing Cushing's syndrome. The fat redistribution in areas such as the face, neck, and trunk is a direct result of cortisol's effects on metabolism and fat storage.

Weight loss, skin hyperpigmentation, and excessive thirst are not typical symptoms of Cushing's syndrome and may be associated with other conditions instead. Weight loss would more commonly be seen in conditions where there is a lack of cortisol or other hormonal imbalances, while skin hyperpigmentation is more often linked to Addison's disease, an adrenal insufficiency. Excessive thirst, or polydipsia, is usually connected with diabetes or other related conditions rather than Cushing's syndrome specifically.