What are living cells that make up most of the life cells of the epidermis in the spinosum layer called?

The living cells that primarily comprise the spinosum layer of the epidermis are referred to as prickle cells. This term is used because of the appearance of these cells under a microscope, where they show intercellular connections that can resemble spines or prickles, thus the name "prickle cells."

In the spinosum layer, these cells play an essential role in the overall structure of the epidermis and help provide strength and flexibility to the skin. Additionally, they are involved in the initial process of keratinization, which is vital for skin barrier function.

Understanding the roles of these prickle cells enhances one's knowledge of skin anatomy and physiology, particularly in the context of the epidermal layers and their function in protection and regeneration.