In which layer of the skin is eleidin found?

Eleidin is a clear, protein-rich substance found specifically in the stratum lucidum, a layer of the skin that is situated between the stratum granulosum and the stratum corneum. This layer is primarily present in thick skin areas, such as the palms of the hands and soles of the feet. Eleidin acts as a precursor to keratin and contributes to the process of keratinization, which is vital for the skin’s barrier function and its ability to protect underlying structures.

The stratum lucidum serves as an additional layer of protection, providing certain areas of the skin with extra resilience and translucence. This unique composition of the stratum lucidum, including eleidin, distinguishes it from other layers of the epidermis, which have different cellular structures and functions, such as producing and storing keratin (as seen in the stratum granulosum) or being the most superficial layer (the stratum corneum) where dead cells are shed.